Normal bone density but loss of muscle and abnormal bone geometry in juvenile idiopathic arthritis

Introduction: Abnormalities of bone have been described in juvenile idiopathic arthritis (JIA). The techniques used in most studies do not allow a three dimensional measurement of bone density and cannot analyze bone geometry. The aim of this study was a detailed analysis of the musculoskeletal system in JIA by determination of bone density, bone geometry and muscle cross sectional area and strength as the most important factor in bone development and maintenance. Methods: The technique of peripheral quantitative computed tomography was used in a cross sectional study on 57 children suffering from juvenile idiop…