Prospective comparative study of Fusidic acid, Vancomycin and Cefuroxime, in prophylactic use in T.H.R. and T.K.R. Early results

Fragestellung: Evaluation of postoperative infections in T.H.R. and T.K.R., after randomized prophylactic use of Fusidic acid, Vancomycin and Cefuroxime and assessment of their side effects. Methoden: From December 2000 to December 2002, 211 patients, were operated on T.H.R. and T.K.R. in Orthopaedic Department of University of Patras. Mean age was 65.8 y. The patients were categorized into three groups (A, B and C). In group A was administrated Fusidic acid 500mg and Cefuroxime 1.5g preoperatively and 2 doses of Fusidic acid 500mg postoperatively. Group B received Vancomycin 1g and Cefuroxime 1.5g preoperativel…