Quantification of Lipids in 1H MR spectra recorded at 3.0 T? Improvements in metabolic studies
G Steidle, J Machann, F Schick, CD Claussen · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2004 · Heft 03
Bibliografische Angaben
Zusammenfassung
Purpose: From a clinical and public health standpoint, determination of amount and distribution of different lipid compartments in humans has become a very important tool in the research of pathogenesis of insulin resistance and diabetes mellitus. Besides ectopic fat (subcutaneous and visceral lipid stores), further compartments as intrahepatic lipids (IHL) or intramyocellular lipids (IMCL) seem to be involved in the development of the disease. Quantification of IMCL? which is aggravated by the overlapping signals of extramyocellular lipids (EMCL) at common field strength of 1.5 T? might make a large profit of h…
