Difficulties of diagnosis and treatment in giant condyloma of Buschke and Löwenstein (GCBL) which led to fatal outcome in a woman

Background: GCBL is a slowly growing, locally destructive verrucous lesion typically appearing in the anogenital region. It is characterized by a large size and tendency to infiltrate the deeper tissues despite its histologically benign appearance. It is regarded as an intermediate lesion between condyloma acuminatum and verrucous carcinoma, but some authors classify these tumors as a regional variant of the verrucous carcinoma. Case report: The authors present a 48-year-old woman who had been treated with condylomatous warts. After unsuccessful local administration of podophyllum, recurrent lesions have been re…