A 78-year-old woman with Osler-disease and amyloidosis

Background: Both amyloidosis and hereditary hemorrhagic telangiectasia (Osler disease) are rare. Involvement of the GI tract is frequent in amyloidosis but the diagnosis is difficult because of the variable clinical manifestations and the nonspecific nature of endoscopic signs. Various endoscopic findings have been reported: fine granular appearance, multiple yellowish-white polypoid protrusions, prominent folds, small mucosal hemorrhages, shallow ulcers, erosions, waxy plaques, and mucosal friability. Simultaneous occurrence of Osler disease and amyloidosis is rare. Case report: A 78-year-old woman with Osler d…