Epidemiological investigation of patients with colorectal polyps

Introduction: Following cardiovascular diseases cancer is the second largest cause of death in the developed countries. Colorectal cancer ranked second among all cancer mortality. Environmental and genetic factors respectively play an important role in the development of the disease. Objective: Our objective was to search for genetic factors which may play a role in the development of the so called sporadic colorectal cancers in groups that are at risk for colorectal cancer (e.g. in patients with colorectal polyps) Patients: Ingested compounds from the environment are metabolized. The majority of the carcinogeni…