Helicobacter pylori: clarithromycin resistance and eradication rates in Szeged, Hungary – a pilot study

Helicobacter pylori (H. p.) infection can be successfully cured with regimens of multiple antimicrobial agents. Resistance to these antimicrobials, and particularly to metronidazole and clarithromycin (CLA), is a leading cause of treatment failure. Aim. To assess the efficacy of different eradication therapies in H. p.-infected patients in relation to the CLA resistance (CLA-R) of H. p. strains. Patients. 107 H. p.-infected adults with peptic ulcer, erosive gastroduodenitis or nonulcer dyspepsia. 47 of them carried H. p. with CLA-R. Samples from a group of 60 pts exhibited CLA-sensitivity (CLA-S). Methods. Genot…