Expression of matrilin-2 in liver cirrhosis and hepatocellular carcinoma
E Szabó, C Páska, C Lódi, E Batmunkh, Á Holczbauer, É Korpos, F Deák, I Kiss, A Kiss, Z Schaff · Zeitschrift für Gastroenterologie · 2005 · Heft 05
Bibliografische Angaben
Zusammenfassung
Introduction/Aim: Although fibrous tissue is represented at low level in normal liver, ECM modifications have serious consequences in liver diseases, being a part of frontier between blood flow and parenchyma. Matrilins are constituents of the ECM, however their pathophysiological role as well as distribution in liver diseases has not yet been studied. Considering that matrilins have been found to play role in cell growth and tissue remodeling, their possible involvement in carcinogenesis has been raised. Our goal was to study the expression of Matrilin-2 by real-time PCR, immunohistochemistry and Western blot a…
