TMS in treatment of patients with neurogenic pain-pretreated with opioids

Questions: The results of TMS-application in patients with neurogenic pain are very different. In most of the cases the groups are small (i.e. n=2) or it is not clear if the patients were treated by opioids before stimulation. So we investigated the effects of variant TMS-Stimulation in comparison with single opioid treatment. Methods: Two groups were used. The first (n=7) contented patients already being a few weeks in treatment with opioids and not satisfied. TMS was used in following variants; Sham.spool, 1Hz-stimulation and at least 10Hz-stimulation. Each stimulation was given with distance of 6 to 8 weeks t…