Correlation between metabolic alterations in 1H-MR Spectroscopy and epileptic activity in patients with temporal lobe epilepsy
T Hammen, M Dölken, M Schwarz, F Kerling, T Engelhorn, A Stadlbauer, O Ganslandt, C Nimsky, M Buchfelder, A Doerfler, H Stefan · Klinische Neurophysiologie · 2006 · Heft 03
Bibliografische Angaben
Zusammenfassung
Introduction: In the following study the degree of metabolite alterations in 1H-MR Spectroscopy (1H-MRS) were correlated to findings of intensive video-EEG monitoring and duration of clinical features in patients with temporal lobe epilepsy (TLE). Patients and methods: 14 TLE patients investigated by 1H-MRS were analysed by: number of clinical seizures, duration of clinical symptoms, frequency of interictal epileptiform discharges (IEDs) and ictal activity.Single Voxel Spectroscopy was carried out in temporomesial structures (Abb. 1). Spectral post processing was carried out by LCModel. Pearson Correlation Coeff…