Characterization of the effect of associative cortical and peripheral nerve stimulation on the somatosensory evoked potentials and tactile discrimination performance in human subj…
D Zeller, V Litvak, R Oostenveld, E Maris, A Cohen, A Schramm, H Pratt, J Classen · Klinische Neurophysiologie · 2006 · Heft 03
Bibliografische Angaben
Zusammenfassung
Repetitive median nerve stimulation combined with transcranial magnetic stimulation (TMS) over the contralateral postcentral region (paired associative stimulation, PAS) may induce changes in the amplitude of the P25 component of median nerve somatosensory evoked potentials (MN-SSEP). Here we used 64-channel electroencephalography (EEG) to reveal the early cortical MN-SSEP source(s) that is modified by PAS. In addition, spatial two-point discrimination was tested one day before (day1), immediately after (day2) and one day after (day3) PAS-intervention to assess possible changes of tactile sensitivity correspondi…