Serologic markers as predictors of complicated Crohn's disease

Background: Various disease-specific serum-antibodies were described in patients with inflammatory bowel disease (IBD) that can predict the development of IBD. Serologic markers predicting the natural course of the disease could be helpful in either the decision of choice of different immunsuppressive treatments or in the follow-up of the patients. The aim of our study was to analyze the positivity of serologic markers and the severity and natural course of Crohn's disease. Methods: 65 patients with verified Crohn's disease were recruted into the study (26 men and 39 women, median age of 32,8 year). All enrolled…