Symptoms improve in a patient with Cogan's syndrome after escalation therapy with intravenous ultra high-dosage glucocorticoids

Objectives: Cogan's syndrome was first described as a syndrome of non-syphilitic interstitial keratitis with vertigo, tinnitus, and profound deafness. It is a rare autoimmunological disease with inflammation of inner ear and eye structures. The disease is progressive and can lead to a complete loss of hearing and bilateral vestibulopathy within a few days. In addition, inflammation of the blood vessels can induce systemic vasculitis. As the disease is often rapidly progressive and organ damage can be irreversible, early diagnosis and adequate treatment is important. Case: Here, we present the case of a 31-year-o…