The differential diagnostic value of video-oculography in the early differentiation of PSP-P and IPD

Objectives: Recent studies have suggested a further differentiation of PSP in Richardson's Syndrome (RS) and PSP-Parkinsonism (PSP-P). On clinical grounds, early PSP-P is hard to distinguish from Idiopathic Parkinson's disease (IPD). Although vertical gaze palsy is one of the core features in the diagnosis of progressive supranuclear palsy (PSP), it is reported to occur later if at all in PSP-P compared to RS. The aim of this study was to search for possibly early oculomotor abnormalities in the PSP-P subset out of a sample of PSP patients via video-oculography (VOG) and to compare these findings with those of R…