CareLit Fachartikel
Breast Cancer, inflammation and proliferation
M Raab, Y Mattheß, M Kaufmann, K Strebhardt · Geburtshilfe und Frauenheilkunde · 2009 · Heft 02
Dokument
913978
CareLit-ID
Jahr
2009
Publikation
PDF
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Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Breast cancer is the most frequent malignant tumor of women in Europe and the United States. Standard treatment modalities have improved the overall outlook and quality of life for women with breast cancer; however, the fact that 40% still die of this illness highlights the need for new therapeutic approaches and identification of new therapeutic targets. While genetic and epigenetic changes in genes that regulate mammary epithelial cell proliferation, survival, polarity and/or differentiation are probable 'initiators' of breast carcinogenesis, several lines of evidence indicate that stromal cell responses in pr…
Schlagworte
Breast
Caspase 8
Apoptosis
Cyclin B1
Tumor
Adenocarcinoma
Cysteine Proteases
Observation
Caspases
Cysteine
Affect
Geburtshilfe und Frauenheilkunde
