MR signal response to hyperoxic and hypercapnic respiratory challenges in the brain at 3 T
A Müller, S Remmele, I Wenningmann, M Soehle, S Flacke, A Kovacs, F Träber, R König, H Clusmann, WA Willinek, H Dahnke, J Gieseke, HH Schild, P Mürtz · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2009 · Heft 01
Bibliografische Angaben
Zusammenfassung
Purpose: To measure and quantify changes of R2* relaxation rates in the brain during breathing of Carbogen and CO2/air and to demonstrate clinical application of the proposed method. Materials and Methods: In nine healthy volunteers and in two patients with a meningioma and a glioblastoma, respectively, cerebral tissue response to respiratory challenges using Carbogen and CO2/air was monitored with a dynamic R2* weighted multi-gradient-echo sequence with high temporal and spatial resolution. The breathing protocol consisted of 3/4/3 minutes of breathing air/gas/air, respectively. The ΔR2* response was analysed v…
