Quality control in transplantation of micron-sized iron oxide particle labelled liver cells by using continuum source atomic absorption spectrometry
N Raschzok, MD Huang, S Florek, H Becker-Roß, N Billecke, NN Kammer, MH Morgül, IM Sauer · Zeitschrift für Gastroenterologie · 2009 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aim: Transplantation of liver cells is a promising approach for treating certain liver diseases. Labelling of hepatocytes prior to transplantation with micron-sized iron oxide particles (MPIOs) enables non-invasive detection of transplanted cells by clinical MR equipment. However, techniques for evaluation of the particle uptake are challenging. Aim of this study was to investigate continuum source atomic absorption spectrometry (CSAAS) for quantification of the particle load of MPIO-labelled liver cells. Methods: Porcine liver cells were isolated from 3 donor pigs and labelled with increasing concentrations of…
