International consensus for neuroblastoma molecular diagnostics: Report from the international neuroblastoma risk grouping (INRG) Biology committee
PF Ambros, IM Ambros, GM Brodeur, M Haber, J Khan, A Nakagawara, G Schleiermacher, F Speleman, R Spitz, WB London, SL Cohn, ADJ Pearson, JM Maris · Klinische Pädiatrie · 2009 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Neuroblastoma serves as a paradigm for utilizing tumour genomic data for determining patient prognosis and treatment allocation. However, prior to the establishment of the International Neuroblastoma Risk Group (INRG) Task Force in 2004, international consensus on markers, methodology, and data interpretation did not exist, compromising the reliability of decisive genetic markers and inhibiting translational research efforts. The objectives of the INRG Biology Committee were to identify highly prognostic genetic aberrations to be included in the new INRG risk classification schema and to develop prec…
