CareLit Fachartikel

Diagnostik und Therapie der hereditären Hämochromatose

G von Figura, H Kulaksiz · DMW - Deutsche Medizinische Wochenschrift · 2009 · Heft 50 · S. 2565-2572

Dokument
916731
CareLit-ID
Jahr
2009
Publikation
PDF
nein
Metadaten
DOI
ja
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Bibliografische Angaben

Zeitschrift
DMW - Deutsche Medizinische Wochenschrift
Autor:innen
G von Figura, H Kulaksiz
Ausgabe
Heft 50 / 2009
Jahrgang 134
Seiten
2565-2572
Erschienen: 2009-12-11 00:00:00
ISSN
0012-0472
DOI
10.1055/s-0029-1243062

Zusammenfassung

Abstract Hereditary hemochromatosis is one of the commonest inherited diseases. The underlying genetic defects lead to an accumulation of iron and subsequent damaging in various organs, especially in the liver. About 14 years ago a genetic test was introduced in Germany that detects hereditary forms of hemochromatosis with a high sensitivity and specificity. This test allows to diagnose hemochromatosis even before end-organ damage is present. The aim is to identify hemochromatosis patients at early disease stages to start a therapy, since an early diagnosis and treatment results in a normal life expectancy. In t…

Schlagworte

Hämochromatose Leberzirrhose Eisen Gentest HFE hemochromatosis cirrhosis iron genetic testing DMW - Deutsche Medizinische Wochenschrift