Perihepatic lymphadenopathy indicates aetiology of acute and chronic liver disease

Aim: In chronic virus hepatitis C the total perihepatic lymph node volume reflects liver histology, viremia, and the immunological response. Therefore, it is helpful in the diagnostic work-up. This study prospectively assessed whether perihepatic lymphadenopathy indicates the aetiology of acute (and chronic) hepatitis which is essential for further management. Methods: In 40 consecutive patients with transaminases higher than 500 U/L without known liver disease the total perihepatic lymph node volume was assessed and compared to the ultrasound findings in 263 patients with chronic liver diseases and 49 healthy c…