CD4 functionality determines outcome in acute HCV re-infection
JC Schulze zur Wiesch, AY Kim, V Kasprowicz, J Timm, T Kuntzen, BE Nolan, S Longworth, A Berical, AW Lohse, RT Chung, V kasprowicz, B Walker, T Allen, GM Lauer · Zeitschrift für Gastroenterologie · 2008 · Heft 01
Bibliografische Angaben
Zusammenfassung
Introduction: There is clinical and epidemiological evidence for at least partially protective immunity after spontaneous resolution of HCV infection in humans. So far the exact correlates of a successful immune response to viral rechallenge have not been determined in the human host and especially the degree of possible HCV cross-protective immunity against heterologous HCV strains needs to be further determined. The current study investigated the immune response of subjects during re-infection with HCV. Methods: For 4 subject in whom we detected a HCV strain distinct from that isolated during the first infecti…
