White Matter Abnormalities in Attention-Deficit/Hyperactivity Disorder: A Diffusion Tensor Imaging Study in Adult Patients
A Konrad, TF Dielentheis, D El Masri, M Bayerl, G Winterer, T Bauermann, G Vucurevic, P Stoeter · Klinische Neurophysiologie · 2008 · Heft 04
Bibliografische Angaben
Zusammenfassung
Objective: Structural and functional neuroimaging studies of subjects with attention-deficit/hyperactivity disorder (ADHD) demonstrated abnormalities primarily in the frontal-striatal circuitry, but also in the corpus callosum, cerebellum, and cortical regions. However, most structural studies were based on volumetric measurements and have been conducted in children. Therefore, the aim of this study was to investigate changes of white matter integrity in adult subjects with ADHD. Methods: N=20 (11 males) ADHD patients and 20 age- and gender matched healthy control subjects underwent a detailed clinical interview…