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Maternal serum ADAM12 levels in IVF pregnancies correlates with PAPP-A, but not with fP-hCG levels during the first trimester

M Ryynanen, H Cuckle, Y Valinen, P Laitinen, L Morin-Papunen · Ultraschall in der Medizin - European Journal of Ultrasound · 2008 · Heft 05

Dokument
921331
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Jahr
2008
Publikation
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Bibliografische Angaben

Zeitschrift
Ultraschall in der Medizin - European Journal of Ultrasound
Autor:innen
M Ryynanen, H Cuckle, Y Valinen, P Laitinen, L Morin-Papunen
Ausgabe
Heft 05 / 2008
Seiten
–
Erschienen: 2008-05-29 00:00:00
ISSN
0172-4614

Zusammenfassung

Background. We wished to investigate the correlation between IVF and Down's syndrome screening analytes, especially ADAM12 and PAPP-A and fβ-hCG during the first trimester. Material and Methods. Retrospective analysis. ADAM12 and PAPP-A and fβ-hCG was measured on 142 consecutive singleton IVF pregnancies and compared with 186 naturally occurring singleton pregnancies during the first trimester. Results. We derived MoM's and weight correction equations for all three analytes from the subjects and controls. The median values were: ADAM12=1.165 MoM, PAPP-A=0.732 MoM, and fβ-hCG=0.902 MoM. Based on the log SDs (0.21…

Schlagworte

ADAM12 Down syndrome screening IVF Papp-A Fβ-Hcg During First Trimester Screening Pregnancies Correlation Between Analytes Singleton Ultraschall in der Medizin - European Journal of Ultrasound