Immune response as a regulator of fetal growth
M Stojanovic, SA Sljivic, I Stojkovic-Eferica · Ultraschall in der Medizin - European Journal of Ultrasound · 2008 · Heft 05
Bibliografische Angaben
Zusammenfassung
Objectives and Aim: The equilibrium of maternal immune, endocrine and nervous systems during pregnancy is a significant condition for the normal growth and development of the foetus (1). The altered rate of cytokines, hormones and neurotransmitters, influences foetal growth and development, tissue differentiation and organogenesis (2). Some data demonstrate that IGF-I is important in the regulation of both normal and restricted fetal growth in utero, and its action appears to be, at least in part, through an endocrine action. The precise role of growth hormone and insulin in fetal growth restriction remains unce…