Placental and Umbilical Cord Blood Oxidative Stress Level and Telomere Homeostasis in Early Onset Severe Preeclampsia
Emre Baser, Nihal Inandiklioglu, Demet Aydogan Kırmızı, Fedi Ercan, Ayşen Caniklioğlu, Mustafa Kara, Taylan Onat, Ethem Serdar Yalvac · Zeitschrift für Geburtshilfe und Neonatologie · 2023 · Heft 02 · S. 112-119
Bibliografische Angaben
Zusammenfassung
Abstract Objective Although the etiopathogenesis of preeclampsia (PE) is unknown, evidence suggests that it may be associated with increased oxidative stress. Studies have shown that oxidative stress can affect DNA fragments called telomeres. However, the interactions of PE, oxidative stress, and telomere length are not clearly known. This study aims to evaluate the oxidative/anti-oxidative stress balance in the placenta and umbilical cord and examine the effect of oxidative stress on telomeres. Materials-Method Cord blood and placental samples were collected from 27 pregnant women with severe PE (280/7–336/7 ge…
