Comparison of liver stiffness assessment by Fibroscan® and Acoustic Radiation Force Impulse Imaging® for the evaluation of liver fibrosis and cirrhosis

Background: Staging of liver fibrosis is an essential part in the management of chronic liver disease. Invasive screening tests like liver biopsy, hepatic venous pressure gradient (HVPG) measurement and Upper-GI-Endoscopy have a significant burden on patients. We compared two different noninvasive methods of liver stiffness measurement (LSM), Transient Elastography (TE; FibroScan®) and Acoustic Radiation Force Impulse Imaging (ARFI; ACUSON Siemens 2000®), with HVPG and histology. Methods: Forty-eight patients (mean age 53±13) with different etiologies of chronic liver diseases were included. Liver cirrhosis (F4)…