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Efficacy and safety of tenofovir disoproxil fumarate (TDF) monotherapy in a European multicenter cohort of nucleos(t)ide experienced patients with chronic hepatitis B virus (HBV)-…

F van Bömmel, RA De Man, P Ferenci, JG Reijnders, JP Bronowicki, A Brodzinski, B Fülöp, H Wedemeyer, K Deterding, A Erhardt, D Hüppe, M Bourlière, C Sarrazin, J Trojan, P Buggisch, J Petersen, U Spengler, K Stein, A Pariente, M Schuchmann, HE Wasmuth, K Rutte… · Zeitschrift für Gastroenterologie · 2010 · Heft 08

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922031
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Jahr
2010
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
F van Bömmel, RA De Man, P Ferenci, JG Reijnders, JP Bronowicki, A Brodzinski, B Fülöp, H Wedemeyer, K Deterding, A Erhardt, D Hüppe, M Bourlière, C Sarrazin, J Trojan, P Buggisch, J Petersen, U Spengler, K Stein, A Pariente, M Schuchmann, HE Wasmuth, K Rutte…
Ausgabe
Heft 08 / 2010
Seiten
–
Erschienen: 2010-08-03 00:00:00
ISSN
0044-2771
DOI
10.1055/s-0030-1264032

Zusammenfassung

Aims: The nucleotide analogue tenofovir disoproxil fumarate (TDF) was shown to be an effective treatment for treatment-naïve patients up to three years of treatment (Marcellin & Heathcote et al, AASLD 2009). The aim of this multicenter cohort study is to study the long term outcome of TDF treatment in patients with previous failure to nucleos(t)ide analogues. Methods: Data from all HBV monoinfected patients treated with TDF monotherapy in 21 European centers were retrospectively analyzed. Inclusion criteria were: age ≥18 years, HBV DNA ≥105 copies/mL and treatment with TDF ≥6 months. HBV DNA (Roche Monitor, LLD…

Schlagworte

Zeitschrift für Gastroenterologie