Association of body mass, smoking and microsatellite status in colorectal cancer: A population-based case-control study (DACHS)
M Hoffmeister, H Bläker, C Toth, E Herpel, B Frank, P Schirmacher, J Chang-Claude, H Brenner · Das Gesundheitswesen · 2010 · Heft 09
Bibliografische Angaben
Zusammenfassung
Introduction: Colorectal cancer is a heterogeneous disease with different pathologic subtypes. In recent studies, body mass index (BMI) was associated with an increased risk of microsatellite-stable (MSS) tumors, but not with microsatellite-instable (MSI-high) tumors. However, after stratification for gender, results were not consistent. Thus, we analysed the association of common risk factors of colorectal cancer with MSI. Methods: We conducted a population-based case-control study in the Rhine-Neckar region (DACHS study), including 1262 patients with colorectal cancer and 1891 controls. MSI status in colorecta…
