MR-Spectroscopy in Dementia
F Träber, W Block, F Jessen, O Gür, W Maier, H Schild · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2010 · Heft 11
Bibliografische Angaben
Zusammenfassung
Purpose: To give an overview on the technical features of magnetic resonance spectroscopy (MRS) in the investigation of demential diseases and to present the results of cross-sectional and longitudinal clinical studies for early diagnosis and follow-up monitoring of cognitive decline using this non-invasive method of metabolic assessment. Materials and Methods: In our initial studies at 1.5 T magnetic field strength, conventional and fast acquisition techniques of proton MR spectroscopic imaging (MRSI) using TR/TE 2000/272ms were employed in the medial temporal lobe (MTL) of 50 patients with Alzheimer disease (A…