Flow Quantification with Arterial Spin Labeling: A Fantom Study

Ziele: Reliable quantification of cerebral blood flow as measured by perfusion-weighted Magnetic Resonance Imaging (MRI) is a still unsolved problem. This is particularly valid for perfusion measurements using the Arterial Spin Labeling (ASL) technique which works without application of contrast medium. In 2009 we developed a dedicated perfusion phantom. Using the known flow parameters of the phantom as a gold standard, we investigated the dependence of (1) amplitude and (2) delay of the MRI signal from the velocity of flow. Methode: The phantom mainly consists out of an MR-compatible dialysator containing a “ca…