45 year old female with hypokalemic rhabdomyolysis due to VIP-producing composite pheochromocytoma

Background: Watery diarrhea, hypokalemia and achlorhydria (WHDA) syndrome due to vasoactive intestinal polypeptide (VIP)-producing extra-pancreatic tumors is rare. Case presentation: We report on a 45-year-old woman who suffered from persistent secretory diarrhea over the last six years and who was admitted to hospital with complaints of muscular weakness and myalgia. Biochemical testing revealed pronounced rhabdomyolysis due to severe hypokalemia. Gastrointestinal evaluation of longstanding diarrhea including endoscopy of the upper and lower gastrointestinal tract and the small intestine did not show any pathol…