No Reason for Hypothyroidism. Five year follow-up results after combined thyroidectomy and Radio Ablation Therapy for differentiated thyroid cancer

Objective: The objective of this study was to compare rhTSH-stimulation versus the standard procedure of thyroid hormone withdrawal as a stimulus for primary radio ablation therapy after thyroidectomy for differentiated thyroid cancer in a clinical applicable setting. Design: Therefore we compared the standard procedure of thyroidectomy followed by four weeks of L-T4 withdrawal and a conclusive ablative activity of 131Iodine with thyroidectomy followed by application of rhTSH and initiation of L-T4 medication and a subsequent radio ablation a few days after surgery. We evaluated parameters of quality-of-life dur…