Induction of human motor cortical long term plasticity by Octo-Pulse Stimulation (OPS)
SJ Groiss, H Mochizuki, H Enomoto, S Nakatani-Enomoto, K Nakamura, A Yoshihara, T Furubayashi, Y Sugiura, T Kujirai, Y Ugawa · Klinische Neurophysiologie · 2012 · Heft 03
Bibliografische Angaben
Zusammenfassung
Objective: Repetitive quadri-pulse transcranial magnetic stimulation (QPS) has recently been shown to induce powerful bidirectional plasticity of the human primary motor cortex (M1). However, the duration of its aftereffects may still be too short to be applied as a clinical therapeutic tool. We hypothesized that increasing the number of pulses to eight (Octo-Pulse Stimulation: OPS) within one burst prolongs the duration of aftereffects. Methods: In ten healthy subjects the effects of higher and lower frequency OPS of M1 on M1 excitability were compared with those of QPS. Motor evoked potentials were used as mea…