Alpha-Sync; a prospective randomized controlled non-invasive alternating current stimulation study in patients with optic neuropathy

Introduction: Neuroplasticity is the ability of the nervous system to change structurally and functionally as a result of neuronal activity. Repetitive transorbital alternating current stimulation (rtACS) can simulate neuronal activity and entrain rhythmic brain activity in healthy subjects and improve visual field size in patients with optic nerve damage. Prosepctive randomized controlled studies are necessary to provide evidence of clinical efficiency. Methods: Electroencephalographic (EEG) power spectra were assessed to determine the association between days of stimulation and changes in alpha-activity over t…