Lesion analyses confirm the importance of left-hemispheric fronto-parieto-networks for praxis and language functions in acute stroke

We performed a voxel-based lesion-symptom mapping (VLSM) for a variety of cognitive parameters related to language and praxis functions in a large cohort of acute stroke patients. 144 stroke patients were tested with a newly developed cognitive bedside screening. Mainly due to bilateral strokes and left-handedness only 106 patients were included in the VLSM analysis using MRIcron. Voxel-based lesion-symptom mapping in this large sample of acute stroke patients with right- (n=56, RH-stroke) and left- (n=50, LH-stroke) hemispheric lesions confirmed the pivotal role of the left hemisphere for language and praxis as…