Pallidal gamma-band oscillatory activity reflects modulation of motor gain according to behavioral requirements in dystonia patients

Introduction: Complementing previous data on the role of the globus pallidus internus (GPi) in error-detection, the present study focuses on the interplay between changes in oscillatory activity and the behavioral requirements of suppression and selection of responses in a rection-time conflict task, which elicits laterality mistakes in the motor responses. Method: We recorded local field potentials (LFPs) bipolarly from adjacent contact pairs located in the GPi in nine patients undergoing deep brain stimulation for therapy resistant idiopathic dystonia during performance of a flanker task. Changes in response-l…