Angiopoietin-related growth factor in the self-contained population of Sorbs
T Ebert, S Kralisch, U Lößner, B Jeßnitzer, M Stumvoll, M Fasshauer, A Tönjes · Diabetologie und Stoffwechsel · 2012 · Heft 05
Bibliografische Angaben
Zusammenfassung
Objective: Angiopoietin-related growth factor (AGF) was recently introduced as a novel liver-derived protein with insulin-sensitizing and anti-obesity effects in mice. In the current study, we investigated circulating AGF levels in the self-contained population of Sorbs in eastern Saxony. Patients and Measurements: AGF was determined by ELISA in a cohort of 818 Sorbs. AGF was correlated to clinical and biochemical measures of renal function, glucose and lipid metabolism, as well as markers of inflammation. Results: Patients with diabetes mellitus type 2 had significantly higher AGF serum levels (49.6µg/l) as com…