Copeptin serum levels are decreased in gestational diabetes mellitus

Objective: Copeptin, a surrogate marker of circulating vasopressin, was recently introduced as a novel biomarker upregulated in type 2 diabetes mellitus (T2DM). In the current study, we investigated serum concentrations of copeptin in gestational diabetes mellitus (GDM). Research design and methods: Circulating levels of copeptin were measured in 79 women with GDM as compared to 79 healthy, gestational age-matched, pregnant controls using an immunoluminometric assay (ILMA). Furthermore, serum concentrations of copeptin were correlated to biochemical and clinical markers of glucose and lipid metabolism, renal fun…