Milk-CLA is a biomarker for traditional farm milk but is not responsible for the allegro-protective farm milk effect in a murine model of airway inflammation

Cross-sectional epidemiological studies have demonstrated that farm milk from traditional farm settings in alpine regions and different rural non-alpine regions possesses allergo-protective properties. We aimed to elucidate possible biomarkers characteristic for farm milk by comparing farm and dairy milk samples collected with the “Protection against Allergy Study in Rural Environments (PASTURE)/Mechanisms of early life protection against allergy (EFRAIM)-Study” for their fatty acid pattern. In addition, we aimed to analyze possible candidates for their allegro-protective capacities in an experimental approach.…