Interactions of inhaled particles with lung tissue – to enter or not to enter, that is the question

Combustion generated nanoparticles or nanoparticles from the environment everybody is constantly exposed to. We all breathe the air, hence air quality is an issue. A big part of these nanoparticles is of carbonaceous origin and, hence, most health relevant. One wonders how they are able to deeply penetrate into our organism. Environmental and combustion generated nanoparticles may enter our organism mainly by inhalation; hence, the main portal of entry is the lung – we cannot stop breathing. Most of the nanoparticles entering via oral way, will pass through the gastro-intestinal tract, the second portal of entry…