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Mussel mimetic tissue adhesive (mussel glue) for fetal membrane repair in vivo

N Ochsenbein-Kölble, AS Kivelio, P Dekoninck, M Perrini, C Brubaker, DG Barrett, P Messersmith, E Mazza, J Deprest, M Ehrbar, R Zimmermann · Zeitschrift für Geburtshilfe und Neonatologie · 2013 · Heft 11

Dokument
929784
CareLit-ID
Jahr
2013
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Zeitschrift für Geburtshilfe und Neonatologie
Autor:innen
N Ochsenbein-Kölble, AS Kivelio, P Dekoninck, M Perrini, C Brubaker, DG Barrett, P Messersmith, E Mazza, J Deprest, M Ehrbar, R Zimmermann
Ausgabe
Heft 11 / 2013
Seiten
–
Erschienen: 2013-11-12 00:00:00
ISSN
0948-2393

Zusammenfassung

Introduction: Iatrogenic preterm prelabour rupture of the fetal membranes (iPPROM) remains the Achilles heel of fetoscopic procedures. The aim was to evaluate and compare the sealing properties of a mussel-mimetic tissue adhesive (mussel glue) with fibrin glue on punctured fetal membranes in the rabbit model. Material and methods: Fetal membrane defects were created by a 14G needle puncture at day 23 and closed with mussel glue alone (N = 10), mussel glue with decellularized amnion scaffold (DAM; N = 10) or commercially available fibrin glue with DAM (N = 15) or left unclosed (positive control; N = 11). Ninety-t…

Schlagworte

Zeitschrift für Geburtshilfe und Neonatologie