Preliminary results of the MORE PrePARd Study (Microparticle Orientated Risk Evaluation in the Prediction of Preeclampsia Among Risk graviDas): a multicenter prospective prognosti…

Background: Preeclampsia (PE) is a potentially dangerous pregnancy pathology contributing to higher worldwide mortality and morbidity. The negative influence of syncytiotrophoblastic microparticles (STBMs) on the placenta and maternal endothelia is thought to play a key role in generating the inflammatory effects that lead to PE symptoms. Doppler sonography of the uterine arteries assists in identifying a risk population but is featured by a low positive predictive value. Aim: Aim of this study is to evaluate whether STBMs can serve as an accessory marker to conventional Doppler sonography to better identify pre…