Mapping of Broca's region using repetitive transcranial magnetic stimulation in correlation to functional and structural imaging

Objective: Broca's area in the left hemisphere is macro-anatomically defined by the pars opercularis and the pars triangularis of the inferior frontal gyrus, represented in cytoarchitectonic Area 44 and Area 45 respectively. Beyond speech production in general, Broca's area is supposed to be linked to differentiated functional roles in language processing. The objective of our study is to combine complementary data from functional and structural-anatomical imaging with the electrophysiological method of transcranial magnetic stimulation (TMS) in order to individually map the Broca's region within the speech netw…