Iterative reconstruction: Improvement of image quality for dynamic CT brain perfusion imaging

Zielsetzung: To quantify impact of iterative reconstruction (iDose) on image noise, increase of SNR and CNR of grey and white brain matter and to ivestigate radiation dose savings by evaluation of stability of two PCT parameters (rCBV in iMTT) as descriptors of the tissue at risk and of the infarct core. Material und Methodik: CTP was obtained in 27 consecutive patients using a 256- slice CT (128 detector rows, flying z- focus, 8-cm detector width, 80 kV, 120 mAs, 20 measurements, 1 CT image/2.5 s). Images were reconstructed with filtered backprojection (FBP) and five different levels of IR (LD 1- LD 5). Noise,…