Serum levels of the adipokine adipocyte fatty acid binding protein are increased in chronic and acute renal dysfunction
T Ebert, LM Hopf, U Wurst, A Bachmann, U Lößner, J Kratzsch, JU Stolzenburg, A Dietel, J Beige, M Anders, I Bast, M Blüher, M Stumvoll, M Fasshauer, S Kralisch · Diabetologie und Stoffwechsel · 2014 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background and aims: Adipocyte fatty acid binding protein (AFABP) has been introduced as a circulating adipokine which is positively associated with the development of the metabolic syndrome, diabetes mellitus, and cardiovascular disease. We hypothesized that AFABP also increases with deteriorating renal function. Methods: Serum AFABP levels were quantified by enzyme linked immunosorbent assay in 532 patients with chronic kidney disease (CKD) covering the whole spectrum of estimated glomerular filtration rate (eGFR) categories from G1 to G5 (study population 1). Furthermore, AFABP was measured in 32 patients bef…
