T1-mapping magnetic resonance imaging for the detection of chronic lung allograft dysfunction – initial results
J Renne, P Lauermann, J Hinrichs, C Schönfeld, S Sorrentino, M Gutberlet, P Jakob, A Haverich, G Warnecke, F Wacker, T Welte, J Gottlieb, J Vogel-Claussen · Pneumologie · 2014 · Heft 06
Bibliografische Angaben
Zusammenfassung
Background: Bronchiolitis obliterans syndrome (BOS) is the major limiting factor for long-term survival after lung transplantation, However, early markers for the detection are missing. Aims and objectives: T1 mapping MRI of the lungs is evaluated for the detection of chronic lung allograft dysfunction in patients following double-lung transplantation. Methods: Fifty-one double-lung allograft recipients were included and gave written informed consent. BOS was classified with spirometry and patients were divided into three groups: BOS 0, BOS0 p and late stages (BOS1 – 3). Coronal T1 maps of the lungs were acquire…