Prognostic value of pretherapeutic 68Ga-PSMA-11-PET based imaging parameters in mCRPC patients treated with PSMA radioligands
Laya Rahbar Nikoukar, Robert Seifert, David Ventura, Philipp Schindler, Martin Bögemann, Kambiz Rahbar, Wolfgang Roll · Nuklearmedizin - NuclearMedicine · 2025 · Heft 01 · S. 7-12
Bibliografische Angaben
Zusammenfassung
Abstract Purpose This study aims to evaluate the prognostic significance of various previously reported PSMA-PET parameters in patients undergoing 177Lu-PSMA radioligand therapy (RLT). While individual studies have investigated the prognostic value of one or few of these factors, comprehensive analyses are rare. Methods Data of 82 patients undergoing 177Lu-PSMA-radiologand-therapy (RLT) were analyzed. Total tumor volume (tumor volume), average SUVmean of all tumor lesions (SUVmean) and the quotient of sum of SUVmean of all tumor lesions to SUVmean of the parotid glands (tumor-parotid-ratio; TPR) and of the kidne…
