PSMA – Targeted Clinical Molecular Imaging of Atherosclerosis: Correlation with Cardiovascular Risk Factors
Julia K. Baude, Felix M. Mottaghy, Thorsten Derlin, Alexander Fischer, Alexander Heinzel, Jan Bucerius · Nuklearmedizin - NuclearMedicine · 2025 · Heft 01 · S. 13-21
Bibliografische Angaben
Zusammenfassung
Abstract Aim The early diagnosis of atherosclerotic changes to prevent ischemic events represents a clinical challenge. Prostate-specific membrane antigen (PSMA) as an established diagnostic in the field of prostate cancer also appears to detect neovascularization and inflammation in other diseases. We hypothesized that it might be also suited for detection of inflammation in atherosclerosis. Methods We analyzed data of 78 prostate cancer patients who received a PSMA ligand PET/CT for re-staging. The cardiovascular risk factors (CVRF) of each patient were documented. Target-to-background-ratios (TBR) were calcul…
