Treatment of PPROM with oligo/anhydramnion colonized by multi-resistant bacteria with continuous amnioinfusion and antibiotic administrations through subcutaneously implanted intr…

Objective: Bacterial infection is one of the main causes of preterm premature rupture of membranes (PPROM) leading to preterm delivery, pulmonary hypoplasia, sepsis, and joint deformities. Expectant management, broad-spectrum antibiotics and antenatal corticosteroids are routinely used in this condition with very limited success to prevent bacteraemia, chorioamnionitis, funisitis and intra-amniotic infection syndrome. Method: Here we report a case in which we attempted to treat a PPROM at 26/3th weeks of gestation with anhydramnion colonized by multi-resistant Klebsiella. The perinatal port- system was implanted…