Prenatal screening for trisomy 21

Introduction: Down syndrome is responsible of different anatomical malformations and mental retardation. A growingbody of evidence-based studies has demonstrated that fetal nuchal translucency can be a powerful prenatal screening tool and combined with first trimester serum markers, it can be incredibly promising in near future. Objective: The aim of our study was to study the strategies of prenatal screening for trisomy 21 and evaluate its results. Methods: Retrospective study conducted at the service A of the maternity and neonatology center of Tunis during a period of 10 years. We included all cases of trisom…